Article
Association of genetic polymorphisms of chemokines and their receptors with clearance or persistence of hepatitis C virus infection.
British journal of biomedical science - 1 Jan 2019
El-Bendary M, Neamatallah M, Elalfy H, Besheer T, El-Setouhy M, Youssef M M, Zein M, Elhammady D, Hegazy A, Esmat G
Abstract excerpt
BACKGROUND: Polymorphisms of certain genes may have an effect on either persistence of infection or spontaneous clearance of hepatitis C virus (HCV). We hypothesized that one or more variants of chemokines (CCL2 and CCL5) and chemokine receptors (CC chemokine receptor type 2 [CCR2]) genes are associated with the susceptibility to HCV infection. METHODS: We recruited 1460 patients with chronic HCV (CHC), 108...
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