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Article

Design strategy for a novel electrochemically active-inactive switching molecular beacon based on Hemin for SNPs and insulin detection directly in homogenous solution.

Talanta - 1 Dec 2018

Dai Shiyan, Zhang Wei, Shao Shuang, Tang Yujiao, Shao Lin, Liu Ting, Cheng Guifang, He Pingang, Fang Yuzhi

Abstract excerpt

Herein, a novel and convenient electrochemically active-inactive switching molecular beacon based on hemin (Hs-MB) has been designed for easy discrimination of single nucleotide polymorphisms (SNPs) and sensitive detection of insulin. The electrochemically active changing capability of Hs-MB is based on two identical hemin groups labeled at both ends of MB sequence in dimer or monomer forms depending on the...

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Identifiers

PMID: 30172515
DOI: 10.1016/j.talanta.2018.08.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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