Genetic variation analysis in a follow-up study of gastric cancer precursor lesions confirms the association of MUC2 variants with the evolution of the lesions and identifies a significant association with NFKB1 and CD14.

doi:10.1002/ijc.31839

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Article

Genetic variation analysis in a follow-up study of gastric cancer precursor lesions confirms the association of MUC2 variants with the evolution of the lesions and identifies a significant association with NFKB1 and CD14.

International journal of cancer - 1 Dec 2018

Companioni Osmel, Bonet Catalina, García Nadia, Ramírez-Lázaro María José, Lario Sergio, Mendoza Jorge, Adrados Mª Magdalena, Poves Elvira, Espinosa Laura, Pozo-Kreilinger José Juan, Ortega Luís, Bujanda Luis, Cosme Angel, Ferrández Angel, Muñoz Guillermo, Cuatrecasas Miriam, Elizalde Ignasi, Andreu Victoria, Paules Mª José, Madrigal Beatriz, Barrio Jesús, Berdasco María, Calvet Xavier, Sanz-Anquela José Miguel, Gisbert Javier P, González Carlos A, Sala Núria

Abstract excerpt

Gastric carcinogenesis proceeds through a series of gastric cancer precursor lesions (GCPLs) leading to gastric cancer (GC) development. Although Helicobacter pylori infection initiates this process, genetic factors also play a role. We previously reported that genetic variability in MUC2 is associated with the evolution of GCPLs. In order to replicate previous results in an independent sample series and to...

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PMID: 30171605
DOI: 10.1002/ijc.31839

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MUC2
NFKB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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