Article
Lipid peroxidation biomarkers for evaluating oxidative stress in equine neuroaxonal dystrophy.
Journal of veterinary internal medicine - 1 Sept 2018
Finno Carrie J, Estell Krista E, Winfield Laramie, Katzman Scott, Bordbari Matthew H, Burns Erin N, Miller Andrew D, Puschner Birgit, Tran Cecilia K, Xu Libin
Abstract excerpt
BACKGROUND: Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is a neurodegenerative disorder affecting genetically predisposed foals maintained on an α-tocopherol (α-TOH) deficient diet. Currently no antemortem diagnostic test for eNAD/EDM is available. HYPOTHESIS: Because α-TOH deficiency is associated with increased lipid peroxidation, it was hypothesized that F2 -isoprostanes (F2...
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