Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Etiology Study of Ten Chinese Families with Nonsyndromic Hearing Loss.

Neural plasticity - 1 Jan 2018

Hu Songqun, Sun Feifei, Zhang Jie, Tang Yan, Qiu Jinhong, Wang Zhixia, Zhang Luping

Abstract excerpt

Nonsyndromic hearing loss has been shown to have high genetic heterogeneity. In this report, we aimed to disclose the genetic causes of the subjects from the ten Chinese deaf families who did not have pathogenic common genes/mutation. Next-generation sequencing (NGS) of 142 known deafness genes was performed in the probands of ten families followed by cosegregation analysis of all family members. We identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to China
Share to Deafness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CDH23 gene

Share to High-Throughput Nucleotide Sequencing

Share to Mutation

Share to Pedigree

Source

Open in PubMed Open full text

Identifiers

PMID: 30123251
DOI: 10.1155/2018/4920980
PMCID: PMC6079373

Genes

CDH23
EYA4
LOXHD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Etiology Study of Ten Chinese Families with Nonsyndromic Hearing Loss.PMID 30123251Read ↗

Clinical and genetic study of 12 Chinese Han families with nonsyndromic deafness.Semantic proximity Read ↗

Variant analysis of 92 Chinese Han families with hearing loss.Semantic proximity Read ↗

Next-generation sequencing identifies rare pathogenic and novel candidate variants in a cohort of Chinese patients with syndromic or nonsyndromic hearing loss.Semantic proximity Read ↗

Molecular diagnose of a large hearing loss population from China by targeted genome sequencing.Semantic proximity Read ↗

Whole Exome Sequencing of Six Chinese Families With Hereditary Non-Syndromic Hearing Loss: A Genetic Etiology StudySemantic proximity Read ↗

Genetic screening of a Chinese cohort of children with hearing loss using a next-generation sequencing panel.Semantic proximity Read ↗

Clinical and genetic study of twelve Chinese Han families with non-syndromic deafnessSemantic proximity Read ↗

Genetic etiology study of the non-syndromic deafness in Chinese Hans by targeted next-generation sequencing.Semantic proximity Read ↗

Molecular etiology of hereditary deafness using next generation sequencing in northwest ChinaSemantic proximity Read ↗

Targeted Next-Generation Sequencing Successfully Detects Causative Genes in Chinese Patients with Hereditary Hearing Loss.Semantic proximity Read ↗

Genetic Screening of a Chinese Cohort of Children with Hearing Loss using a Next-Generation Sequencing PanelSemantic proximity Read ↗

Comprehensive genetic testing of Chinese SNHL patients and variants interpretation using ACMG guidelines and ethnically matched normal controlsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.