Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblasts

13 Aug 2018

Abstract excerpt

BACKGROUND: Glioblastoma (GBM) is a tumor of the central nervous system. After surgical removal and standard therapy, recurrence of tumors is observed within 6-9 months because of the high migratory behavior and the infiltrative growth of cells. Here, we investigated whether carnosine (β-alanine-l-histidine), which has an inhibitory effect on glioblastoma proliferation, may on the opposite promote invasion as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldose Reductase and Taurine
Share to Biochemical effects in animals
Share to Healthcare and Venom Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30123089
DOI: 10.1186/s12935-018-0611-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carnosine selectively inhibits migration of IDH-wildtype glioblastoma cells in a co-culture model with fibroblastsPMID 30123089Read ↗

Lactate cannot replace glucose for maintaining the viability of mouse and human glioma cellsSemantic proximity Read ↗

Primary fibroblast co-culture stimulates growth and metabolism in Sdhb-impaired mouse pheochromocytoma MTT cells.Semantic proximity Read ↗

Development of a 3D Tumor Spheroid Model from the Patient’s Glioblastoma Cells and Its Study by Metabolic Fluorescence Lifetime ImagingSemantic proximity Read ↗

Coculture with astrocytes reduces the radiosensitivity of glioblastoma stem‐like cells and identifies additional targets for radiosensitizationSemantic proximity Read ↗

A Systematic Comparison Identifies an ATP‐Based Viability Assay as Most Suitable Read‐Out for Drug Screening in Glioma Stem‐Like CellsSemantic proximity Read ↗

In Vitro/In Silico Study on the Role of Doubling Time Heterogeneity among Primary Glioblastoma Cell LinesSemantic proximity Read ↗

Radiosensitization of Glioma Cells by Temozolomide (TMZ): A Colony Formation AssaySemantic proximity Read ↗

Methionine dependency of malignant tumors: a possible approach for therapy.Semantic proximity Read ↗

Hypoxia and hypoxia mimetic cooperate to counteract tumor cell resistance to glucose starvation preferentially in tumor cells with mutant p53.Semantic proximity Read ↗

Extracellular Sphingosine-1-Phosphate: A Novel Actor in Human Glioblastoma Stem Cell SurvivalSemantic proximity Read ↗

Glioma cells showing IDH1 mutation cannot be propagated in standard cell culture conditions.Semantic proximity Read ↗

Live-cell calcium imaging of adherent and non-adherent GL261 cells reveals phenotype-dependent differences in drug responses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.