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Article

A simple genetic basis of adaptation to a novel thermal environment results in complex metabolic rewiring in Drosophila.

Genome biology - 20 Aug 2018

Mallard François, Nolte Viola, Tobler Ray, Kapun Martin, Schlötterer Christian

Abstract excerpt

BACKGROUND: Population genetic theory predicts that rapid adaptation is largely driven by complex traits encoded by many loci of small effect. Because large-effect loci are quickly fixed in natural populations, they should not contribute much to rapid adaptation. RESULTS: To investigate the genetic architecture of thermal adaptation - a highly complex trait - we performed experimental evolution on a natural...

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Identifiers

PMID: 30122150
DOI: 10.1186/s13059-018-1503-4
PMCID: PMC6100727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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