Article
Another Chapter of the Right Versus Left Story: Is Primary Tumor Location a Prognostic Feature in RAS Mutant Metastatic Colorectal Cancer?
The oncologist - 1 Feb 2019
Loupakis Fotios, Schirripa Marta, Intini Rossana, Bergamo Francesca, Bertorelle Roberta, Fassan Matteo, Dadduzio Vincenzo, Merigliano Stefano, Pilati Pierluigi, Urso Emanuele Luca Damiano, Cillo Umberto, Rugge Massimo, Lonardi Sara, Zagonel Vittorina
Abstract excerpt
BACKGROUND: The prognostic value of primary tumor location (PTL) in patients with metastatic colorectal cancer (mCRC) was reported by recent analyses in RAS wild-type patients. Here, we investigated the prognostic value of PTL in RAS mutated mCRC patients. MATERIALS AND METHODS: PTL was defined as left or right if distal or proximal to the splenic flexure. Primary endpoint was overall survival (OS) according to...
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