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Article

miR-590-5p suppresses hepatocellular carcinoma chemoresistance by targeting YAP1 expression.

EBioMedicine - 1 Sept 2018

Chen Minjiang, Wu Liming, Tu Jianfei, Zhao Zhongwei, Fan Xiaoxi, Mao Jianting, Weng Qiaoyou, Wu Xulu, Huang Li, Xu Min, Ji Jiansong

Abstract excerpt

BACKGROUND: Resistance to chemotherapeutic treatment is a common phenomenon in cancers, especially in hepatocellular carcinoma (HCC). The Hippo signaling pathway has been demonstrated to play a role in tumor initiation, development, and progression. However, little is known about its roles in the HCC chemoresistance. METHODS: In this study, real-time PCR and western blotting were used to identify the expression...

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Share to ATP-Binding Cassette Transporters
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Doxorubicin

Share to Liver Neoplasms

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Share to Neoplastic Stem Cells

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Share to YAP-Signaling Proteins

Source

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Identifiers

PMID: 30111512
DOI: 10.1016/j.ebiom.2018.08.010
PMCID: PMC6154877

Genes

YAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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