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Article

Integration of bioinformatics and experiments to identify TP53 as a potential target in Emodin inhibiting diffuse large B cell lymphoma.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Nov 2018

Chen Yanxin, Mei Xuqiao, Gan Donghui, Wu Zhengjun, Cao Yanqin, Lin Minhui, Zhang Na, Yang Ting, Chen Yingyu, Hu Jianda

Abstract excerpt

Non-Hodgkin's Lymphoma (NHL) is a group of lymphoid malignancies with unsatisfactory treatment effect in some aggressive subtypes, including diffuse large B cell lymphoma (DLBCL). Emodin is an anthraquinone with potent anti-cancer activities. However, the molecular mechanism of Emodin repressing aggressive NHL remains to be revealed in detail. This study delineated the active mechanism of Emodin action in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lymphoma, Large B-Cell, Diffuse

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Source

Identifiers

PMID: 30096626
DOI: 10.1016/j.biopha.2018.07.168

Genes

DPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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