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Article

Influence of Individual Radiosensitivity on the Adaptive Response Phenomenon: Toward a Mechanistic Explanation Based on the Nucleo-Shuttling of ATM Protein

1 Jul 2018

Abstract excerpt

The adaptive response (AR) phenomenon generally describes a protective effect caused by a “priming” low dose ( d AR ) delivered after a period of time (Δ t AR ) before a higher “challenging” dose ( D AR ). The AR is currently observed in human cells if d AR , Δ t AR , and D AR belong to (0.001-0.5 Gy), (2-24 hours), (0.1-5 Gy), respectively. In order to investigate the molecular mechanisms specific to AR in human...

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PMID: 30093841
DOI: 10.1177/1559325818789836

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