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Article

Characterization of intra- and inter-host norovirus P2 genetic variability in linked individuals by amplicon sequencing.

PloS one - 1 Jan 2018

Sabrià Aurora, Pintó Rosa M, Bosch Albert, Quer Josep, Garcia-Cehic Damir, Gregori Josep, Dominguez Angela, Carol Mónica, Sala-Farré Maria-Rosa, Guix Susana

Abstract excerpt

Noroviruses are the main cause of epidemics of acute gastroenteritis at a global scale. Although chronically infected immunocompromised individuals are regarded as potential reservoirs for the emergence of new viral variants, viral quasispecies distribution and evolution patterns in acute symptomatic and asymptomatic infections has not been extensively studied. Amplicons of 450 nts from the P2 coding capsid...

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Identifiers

PMID: 30092071
DOI: 10.1371/journal.pone.0201850
PMCID: PMC6084935

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