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Article

MicroRNA-30c-5p modulates neuropathic pain in rodents.

Science translational medicine - 8 Aug 2018

Tramullas Mónica, Francés Raquel, de la Fuente Roberto, Velategui Sara, Carcelén María, García Raquel, Llorca Javier, Hurlé María A

Abstract excerpt

Neuropathic pain is a debilitating chronic syndrome that is often refractory to currently available analgesics. Aberrant expression of several microRNAs (miRNAs) in nociception-related neural structures is associated with neuropathic pain in rodent models. We have exploited the antiallodynic phenotype of mice lacking the bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI), a transforming...

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Source

Identifiers

PMID: 30089634
DOI: 10.1126/scitranslmed.aao6299

Genes

BAMBI

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