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Article

Differential expression of miRNAs in the nervous system of a rat model of bilateral sciatic nerve chronic constriction injury

14 May 2013

Abstract excerpt

Chronic neuropathic pain is associated with global changes in gene expression in different areas of the nociceptive pathway. MicroRNAs (miRNAs) are small (~22 nt long) non-coding RNAs, which are able to regulate hundreds of different genes post-transcriptionally. The aim of this study was to determine the miRNA expression patterns in the different regions of the pain transmission pathway using a rat model of...

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PMID: 23673427
DOI: 10.3892/ijmm.2013.1381

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