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Article

Differential Expression of MicroRNAs in Mouse Pain Models

1 Jan 2011

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are short non-coding RNAs that inhibit translation of target genes by binding to their mRNAs. The expression of numerous brain-specific miRNAs with a high degree of temporal and spatial specificity suggests that miRNAs play an important role in gene regulation in health and disease. Here we investigate the time course gene expression profile of miR-1, -16, and -206 in mouse dorsal...

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PMID: 21385380
DOI: 10.1186/1744-8069-7-17

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