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Article

Genetics of primary macronodular adrenal hyperplasia.

Presse medicale (Paris, France : 1983) - 1 Jan 2000

Candida Barisson Villares Fragoso Maria, Pontes Cavalcante Isadora, Meneses Ferreira Amanda, Marinho de Paula Mariani Beatriz, Ferini Pacicco Lotfi Claudimara

Abstract excerpt

Recent advances in molecular genetics investigations of primary macronodular adrenal hyperplasia (PMAH) have been providing new insights for the research on this issue. The cAMP-dependent pathway is physiologically triggered by ACTH and its receptor, MC2-R, in adrenocortical cells. Different mechanisms of this cascade may be altered in some functioning adrenal cortical disorders. Activating somatic mutations of...

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Share to Adrenal Cortex Neoplasms
Share to Adrenal Hyperplasia, Congenital

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30075949
DOI: 10.1016/j.lpm.2018.07.002

Genes

GNAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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