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Article

Genetics of primary macronodular adrenal hyperplasia.

The Journal of endocrinology - 1 Jan 2015

Fragoso Maria Candida Barisson Villares, Alencar Guilherme Asmar, Lerario Antonio Marcondes, Bourdeau Isabelle, Almeida Madson Queiroz, Mendonca Berenice Bilharinho, Lacroix André

Abstract excerpt

ACTH-independent macronodular adrenal hyperplasia is a rare cause of Cushing's syndrome (CS), accounting for <2% of all endogenous CS cases; however it is more frequently identified incidentally with sub-clinical cortisol secretion. Recently, cortisol secretion has been shown to be regulated by ectopic corticotropin, which is in turn produced by clusters of steroidogenic cells of the hyperplastic adrenal nodules....

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Identifiers

PMID: 25472909
DOI: 10.1530/JOE-14-0568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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