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Article

Implications of Janus Kinase 2 Mutation in Embolic Stroke of Unknown Source.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Oct 2018

Trifan Gabriela, Shafi Neelofer, Testai Fernando D

Abstract excerpt

The role of genetic mutations in cerebral ischemia is not completely understood. Among these genetic variations, Philadelphia-negative gain-of-function mutation in the janus kinase 2 (JAK2) protein leads to overexpression of the genes involved in cell growth and proliferation, and has been linked to development of hematological malignancies, specifically, myeloproliferative neoplasms (MPNs; essential...

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Source

Identifiers

PMID: 30056970
DOI: 10.1016/j.jstrokecerebrovasdis.2018.05.052

Genes

JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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