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Article

Lipid droplet and peroxisome biogenesis occur at the same ER subdomains.

Nature communications - 27 Jul 2018

Joshi Amit S, Nebenfuehr Benjamin, Choudhary Vineet, Satpute-Krishnan Prasanna, Levine Tim P, Golden Andy, Prinz William A

Abstract excerpt

Nascent lipid droplet (LD) formation occurs in the endoplasmic reticulum (ER) membrane but it is not known how sites of biogenesis are determined. We previously identified ER domains in S. cerevisiae containing the reticulon homology domain (RHD) protein Pex30 that are regions where preperoxisomal vesicles (PPVs) form. Here, we show that Pex30 domains are also sites where most nascent LDs form. Mature LDs usually...

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Share to Diacylglycerol O-Acyltransferase
Share to Endoplasmic Reticulum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein gamma Subunits

Share to Lipid Droplets

Share to Methyltransferases

Share to Organelle Biogenesis

Share to Peroxisomes

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Source

Open in PubMed Open full text

Identifiers

PMID: 30054481
DOI: 10.1038/s41467-018-05277-3
PMCID: PMC6063926

Genes

RHD
MCTP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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