Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapy

15 Jun 2018

Abstract excerpt

STUDY QUESTION: Does chemotherapy exposure (with or without alkylating agents) or primary diagnosis affect spermatogonial quantity in human prepubertal testicular tissue? SUMMARY ANSWER: Spermatogonial quantity is significantly reduced in testes of prepubertal boys treated with alkylating agent therapies or with hydroxyurea for sickle cell disease. WHAT IS KNOWN ALREADY: Cryopreservation of spermatogonial stem...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Male Reproductive Health Studies
Share to Sperm and Testicular Function
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30052981
DOI: 10.1093/humrep/dey240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spermatogonial quantity in human prepubertal testicular tissue collected for fertility preservation prior to potentially sterilizing therapyPMID 30052981Read ↗

Z-scores for comparative analyses of spermatogonial numbers throughout human developmentSemantic proximity Read ↗

Cryopreservation of testicular tissue or testicular cell suspensions: a pivotal step in fertility preservationSemantic proximity Read ↗

A diagnostic germ cell score for immature testicular tissue at risk of germ cell lossSemantic proximity Read ↗

Mapping the Development of Human Spermatogenesis Using Transcriptomics-Based Data: A Scoping ReviewSemantic proximity Read ↗

Update on fertility restoration from prepubertal spermatogonial stem cells: How far are we from clinical practice?Semantic proximity Read ↗

Spermatogonial stem cells: updates from specification to clinical relevanceSemantic proximity Read ↗

Mesenchymal stem cells promote spermatogonial stem/progenitor cell pool and spermatogenesis in neonatal mice in vitroSemantic proximity Read ↗

Identification and characterization of stem cells in prepubertal spermatogenesis in mice☆☆Supplementary data associated with this article can be found at doi:10.1016/S0012-1606(03)00111-8.Semantic proximity Read ↗

Assessment of fresh and cryopreserved testicular tissues from (pre)pubertal boys during organ culture as a strategy for in vitro spermatogenesisSemantic proximity Read ↗

Cellular Therapy via Spermatogonial Stem Cells for Treating Impaired Spermatogenesis, Non-Obstructive AzoospermiaSemantic proximity Read ↗

New advances on the expansion and storage of human spermatogonial stem cellsSemantic proximity Read ↗

Efforts to create an artificial testis: culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.