Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long non‐coding RNA s in nucleus pulposus cell function and intervertebral disc degeneration

24 Jul 2018

Abstract excerpt

Intervertebral disc degeneration (IDD) is the major cause of low back pain which incurs a significant public-health and economic burden. The aetiology of IDD is complex, with developmental, genetic, biomechanical and biochemical factors contributing to the disease development. Deregulated phenotypes of nucleus pulposus cells, including aberrant differentiation, apoptosis, proliferation and extracellular matrix...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Orthopaedic implants and arthroplasty
Share to Osteoarthritis Treatment and Mechanisms
Share to Spine and Intervertebral Disc Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30039593
DOI: 10.1111/cpr.12483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long non‐coding RNA s in nucleus pulposus cell function and intervertebral disc degenerationPMID 30039593Read ↗

Circular RNAs in nucleus pulposus cell function and intervertebral disc degenerationSemantic proximity Read ↗

The role of miRNA, lncRNA and circRNA in the development of intervertebral disk degeneration (Review)Semantic proximity Read ↗

Circular RNAs in Intervertebral Disc Degeneration: An Updated ReviewSemantic proximity Read ↗

The potential mechanisms and application prospects of non-coding RNAs in intervertebral disc degenerationSemantic proximity Read ↗

Single-Cell and WGCNA Integrative Analysis Reveal the Key Chondrocytes Niches and Pathogenic Genes in Intervertebral Disc DegenerationSemantic proximity Read ↗

The Mechanism and Function of <scp>miRNA</scp> in Intervertebral Disc DegenerationSemantic proximity Read ↗

Role of microRNAs in intervertebral disc degeneration (Review)Semantic proximity Read ↗

Aberrantly expressed long noncoding RNAs in human intervertebral disc degeneration: a microarray related studySemantic proximity Read ↗

tsRNA-04002 alleviates intervertebral disk degeneration by targeting PRKCA to inhibit apoptosis of nucleus pulposus cellsSemantic proximity Read ↗

Potential Role of lncRNAs in Contributing to Pathogenesis of Intervertebral Disc Degeneration Based on Microarray DataSemantic proximity Read ↗

Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cellsSemantic proximity Read ↗

Long non-coding RNA PART1 promotes intervertebral disc degeneration through regulating the�miR‑93/MMP2 pathway in nucleus pulposus cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.