Article
Whole genome SNP analysis suggests unique virulence factor differences of the Beijing and Manila families of Mycobacterium tuberculosis found in Hawaii.
PloS one - 1 Jan 2018
Koster Kent, Largen Angela, Foster Jeffrey T, Drees Kevin P, Qian Lishi, Desmond Edward P, Wan Xuehua, Hou Shaobin, Douglas James T
Abstract excerpt
While tuberculosis (TB) remains a global disease, the WHO estimates that 62% of the incident TB cases in 2016 occurred in the WHO South-East Asia and Western Pacific regions. TB in the Pacific is composed predominantly of two genetic families of Mycobacterium tuberculosis (Mtb): Beijing and Manila. The Manila family is historically under-studied relative to the families that comprise the majority of TB in Europe...
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