Hb Oslo [β42(CD1)Phe→Ile;HBB: c.127T>A]: A Novel Unstable Hemoglobin Variant Found in a Norwegian Patient

doi:10.1080/03630269.2018.1468773

Article

Hb Oslo [β42(CD1)Phe→Ile;HBB: c.127T>A]: A Novel Unstable Hemoglobin Variant Found in a Norwegian Patient

4 Mar 2018

Abstract excerpt

Unstable hemoglobin (Hb) variants are the result of sequence variants in the globin genes causing precipitation of Hb molecules in red blood cells (RBCs). Intracellular inclusions derived from the unstable Hb reduce the life-span of the red cells and may cause hemolytic anemia. Here we describe a patient with a history of hemolytic anemia and low oxygen saturation. She was found to be carrier of a novel unstable...

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