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Hemoglobin Evans Associated with HBA1 Mutation: First Report from Rosario, Argentina.

Hemoglobin - 1 May 2026

Raviola Mariana, Maroni Georgina, Pratti Arianna, Detarsio German Alejandro, Cherichetti María Ángela, Schoepf María Victoria, Gaggioli Osvaldo Stefan, Bonavita Daniela, Casesi Paulina, Ojeda Mara

Abstract excerpt

Hemoglobin Evans is a rare, unstable α-chain variant resulting from a valine-to-methionine substitution at codon 62 (E11) of the α-globin gene, previously reported only in HBA2. We describe the first documented case involving the HBA1 gene (HBA1:c.187G > A), identified in a 3-year-old boy who was evaluated for persistent anemia. Laboratory findings revealed hemolytic anemia with low haptoglobin, a negative Coombs...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42091220
DOI: 10.1080/03630269.2026.2664203

Genes

HBA1
HBA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

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