Article
Association between the HOTAIR Polymorphism and Susceptibility to Lead Poisoning in a Chinese Population.
Biomedical and environmental sciences : BES - 1 Jun 2018
Chen Lin, Zhao Qiu Ni, Qian Xiu Rong, Zhu Bao Li, Ding En Min, Wang Bo Shen, Zhang Heng Dong, Yang Hong
Abstract excerpt
This study explored the association between the lncRNA HOTAIR polymorphism and susceptibility to lead poisoning in a Chinese population. We speculated that lead poisoning caused elevated levels of oxidative stress, which, in turn, activate the HOTAIR gene to cause apoptosis. Three lncRNA HOTAIR tagSNPs (rs7958904, rs4759314, and rs874945) were genotyped by TaqMan genotyping technology in 113 lead-sensitive and...
Read the complete abstract on PubMed