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Article

NS3 Variability in Hepatitis C Virus Genotype 1A Isolates from Liver Tissue and Serum Samples of Treatment-Naïve Patients with Chronic Hepatitis C.

Intervirology - 1 Jan 2018

D'Aliberti Deborah, Cacciola Irene, Musolino Cristina, Raffa Giuseppina, Filomia Roberto, Alibrandi Angela, Benfatto Salvatore, Beninati Concetta, Saitta Carlo, Giosa Domenico, Romeo Orazio, Raimondo Giovanni, Pollicino Teresa

Abstract excerpt

BACKGROUND: Hepatitis C virus (HCV) NS3 resistance-associated substitutions (RASs) reduce HCV susceptibility to protease inhibitors. Little is known about NS3 RASs in viral isolates from the liver of chronic hepatitis C (CHC) patients infected with HCV genotype-1a (G1a). AIM: The objective of this work was to study NS3 variability in isolates from the serum and liver of HCV-G1a-infected patients naïve to...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30021203
DOI: 10.1159/000489307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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