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Article

An insight into the molecular genetics of a uveal melanoma patient cohort.

Journal of cancer research and clinical oncology - 1 Oct 2018

Kennedy Susan, Rice Michael, Toomey Sinead, Horgan Noel, Hennessey Bryan T, Larkin Annemarie

Abstract excerpt

BACKGROUND/AIMS: Uveal melanoma (UM) is a highly aggressive malignancy and presents a clinically significant unmet need in cancer therapeutics. The aim of this study was to identify previously unreported mutations in UM among an Irish cohort of patients which may have potential clinical relevance. METHODS: DNA was extracted from 36 intraocular melanoma patient samples and 4 metastatic melanoma samples among the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30008023
DOI: 10.1007/s00432-018-2705-6

Genes

GNA11
GNAQ
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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