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Article

Erythropoietin alleviates hyperglycaemia-associated inflammation by regulating macrophage polarization via the JAK2/STAT3 signalling pathway.

Molecular immunology - 1 Sept 2018

Cui Jinjin, Zhang Fengyun, Cao Wei, Wang Yongshun, Liu Jingjin, Liu Xinxin, Chen Tao, Li Ling, Tian Jinwei, Yu Bo

Abstract excerpt

BACKGROUND: Erythropoietin (EPO), which is clinically used for renal anaemia, reportedly exerts beneficial pleiotropic effects in atherosclerosis. This aim of this study was to investigate the effects of EPO on macrophage inflammation and polarization under hyperglycaemic conditions and to identify the effects of EPO-treated macrophage supernatants (SNs) on endothelial cell (EC) function. METHODS: Peritoneal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30007232
DOI: 10.1016/j.molimm.2018.05.028

Genes

EPO
JAK2
STAT3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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