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Article

An integrative network-based approach to identify novel disease genes and pathways: a case study in the context of inflammatory bowel disease

13 Jul 2018

Abstract excerpt

BACKGROUND: There are different and complicated associations between genes and diseases. Finding the causal associations between genes and specific diseases is still challenging. In this work we present a method to predict novel associations of genes and pathways with inflammatory bowel disease (IBD) by integrating information of differential gene expression, protein-protein interaction and known disease genes...

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PMID: 30005591
DOI: 10.1186/s12859-018-2251-x

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