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Genetic Susceptibility for Cervical Cancer in African Populations: What Are the Host Genetic Drivers?

Omics : a journal of integrative biology - 1 Jul 2018

Kuguyo Oppah, Tsikai Nomsa, Thomford Nicholas E, Magwali Thulani, Madziyire Mugove G, Nhachi Charles F B, Matimba Alice, Dandara Collet

Abstract excerpt

Human papillomavirus (HPV) is an essential but not a sufficient cervical cancer etiological factor. Cancer promoters, such as host genetic mutations, significantly modulate therapeutic responses and susceptibility. In cervical cancer, of interest have been viral clearing genes and HPV oncoprotein targets, for which conflicting data have been reported among different populations. This expert analysis evaluates...

Topics

Case-Control Studies
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Humans
Uterine Cervical Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30004844
DOI: 10.1089/omi.2018.0075

Genes

CCR2
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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