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Article

FAN1 protects against repeat expansions in a Fragile X mouse model.

DNA repair - 1 Sept 2018

Zhao Xiao-Nan, Usdin Karen

Abstract excerpt

The Fragile X-related disorders (FXDs) are members of a large group of human neurological or neurodevelopmental conditions known as the Repeat Expansion Diseases. The mutation responsible for all of these diseases is an expansion in the size of a disease-specific tandem repeat tract. However, the underlying cause of this unusual mutation is unknown. Genome-wide association studies have identified single...

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Source

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Identifiers

PMID: 29990673
DOI: 10.1016/j.dnarep.2018.07.001
PMCID: PMC6119480

Genes

FAN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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