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Article

Genome-Wide Changes in Protein Translation Efficiency Are Associated with Autism.

Genome biology and evolution - 1 Aug 2018

Rogozin Igor B, Gertz E Michael, Baranov Pasha V, Poliakov Eugenia, Schaffer Alejandro A

Abstract excerpt

We previously proposed that changes in the efficiency of protein translation are associated with autism spectrum disorders (ASDs). This hypothesis connects environmental factors and genetic factors because each can alter translation efficiency. For genetic factors, we previously tested our hypothesis using a small set of ASD-associated genes, a small set of ASD-associated variants, and a statistic to quantify by...

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Identifiers

PMID: 29986017
DOI: 10.1093/gbe/evy146
PMCID: PMC6086092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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