Article
Hepatitis C virus serologic relapse after treatment with direct-acting antivirals is dependent on viral RNA levels in peripheral blood mononuclear cells and the grade of liver cirrhosis.
Archives of virology - 1 Oct 2018
Abd Alla Mohamed Darwish Ahmed, El Awady Mostafa Kamel, Dawood Reham M, Elhawary Mostafa Abdelaziz, Al-Azhari Shabaan Salah, Galal Al-Shazly Gaber Mohamed
Abstract excerpt
The disappearance of hepatitis C virus (HCV) from serum and tissues for 12 weeks after the end of treatment (EOT) with direct-acting antivirals (DAAs) is known as a "sustained virologic response" (SVR) and occurs more frequently in non-cirrhotic patients than in cirrhotic patients. In this study, we evaluated the outcome of HCV treatment with sofosbuvir (SOF) plus ledipasvir (LDV) at both EOT and 12 weeks after...
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