Article
Polymorphisms in TWIST1 and ZEB1 Are Associated with Prognosis of Gastric Cancer Patients.
Anticancer research - 1 Jul 2018
Romero Sandra, Musleh Maher, Bustamante Marco, Stambuk Juan, Pisano Raul, Lanzarini Enrique, Chiong Hector, Rojas Jorge, Castro V Gonzalo, Jara Lilian, Berger Zoltan, Gonzalez-Hormazabal Patricio
Abstract excerpt
BACKGROUND/AIM: Epithelial-mesenchymal transition (EMT) program has been linked as a driver of metastatic dissemination by conferring migratory and invasive capacity to cancer cells. Gastric cancer (GC) patients with tumors expressing altered levels of EMT markers have low survival. This study aimed to assess if polymorphisms of CDH1, TWIST1, SNAIL2, ZEB1 and ZEB2 genes are associated with survival in GC...
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