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Article

Hypoxic CA9 variant as a potential prognostic marker in gastric and breast cancers.

Scientific reports - 24 Apr 2026

Krishnasamy Vignesh, Ralte Lalengkimi, Lalhruaizela Samuel, Ralte Ruby Zothankimi, Vanlalpeka Harvey, Lalrinpuia Benjamin, Kumar Nachimuthu Senthil

Abstract excerpt

Gastric cancer (GC) and breast cancer (BC) are among the most common malignancies worldwide, with significant mortality rates despite advances in diagnosis and treatment. Genetic variants in the hypoxia-inducible factor (HIF) pathway, which plays an important role in tumor microenvironment adaptation, have emerged as potential contributors to cancer susceptibility and prognosis. Our study investigates the role of...

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Source

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Identifiers

PMID: 42032036
DOI: 10.1038/s41598-026-49972-4
PMCID: PMC13275901

Genes

GC
CA9
EGLN1
ABCB1
CDC20B
CDH11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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