Article
Multilocus sequence typing of clinical Borreliella afzelii strains: population structure and differential ability to disseminate in humans.
Parasites & vectors - 28 Jun 2018
Gallais Floriane, De Martino Sylvie J, Sauleau Erik A, Hansmann Yves, Lipsker Dan, Lenormand Cédric, Talagrand-Reboul Emilie, Boyer Pierre H, Boulanger Nathalie, Jaulhac Benoît, Schramm Frédéric
Abstract excerpt
BACKGROUND: Lyme borreliosis in humans results in a range of clinical manifestations, thought to be partly due to differences in the pathogenicity of the infecting strain. This study compared European human clinical strains of Borreliella afzelii (previously named Borrelia afzelii) using multilocus sequence typing (MLST) to determine their spatial distribution across Europe and to establish whether there are...
Topics
- Animals
- Borrelia burgdorferi
- Borrelia burgdorferi Group
- Europe
- Genetic Variation
- Genotype
- Humans
- Ixodes
- Lyme Disease
- Multilocus Sequence Typing