Article
Effectiveness of Ledipasvir/Sofosbuvir and Predictors of Treatment Failure in Members with Hepatitis C Genotype 1 Infection: A Retrospective Cohort Study in a Medicaid Population.
Journal of managed care & specialty pharmacy - 1 Jul 2018
Kouris George, Hydery Tasmina, Greenwood Bonnie C, Lavitas Pavel, Price Mylissa, Clements Karen, Alper Caroline J, Lenz Kimberly, Jeffrey Paul L
Abstract excerpt
BACKGROUND: The primary goal of therapy for patients with chronic hepatitis C virus (HCV) infection is eradication of HCV ribonucleic acid, which is predicted by achievement of sustained virologic response at 12 weeks (SVR12). Ledipasvir/sofosbuvir was approved by the FDA in 2014 and 2015 as a once-daily regimen for the treatment of HCV genotype 1 and HCV genotypes 4, 5, and 6, respectively. Although its efficacy...
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