Article
Effectiveness of Ledipasvir-Sofosbuvir Combination in Patients With Hepatitis C Virus Infection and Factors Associated With Sustained Virologic Response.
Gastroenterology - 1 Dec 2016
Terrault Norah A, Zeuzem Stefan, Di Bisceglie Adrian M, Lim Joseph K, Pockros Paul J, Frazier Lynn M, Kuo Alexander, Lok Anna S, Shiffman Mitchell L, Ben Ari Ziv, Akushevich Lucy, Vainorius Monika, Sulkowski Mark S, Fried Michael W, Nelson David R
Abstract excerpt
BACKGROUND & AIMS: The combination of ledipasvir and sofosbuvir has been approved for treatment of genotype 1 hepatitis C virus (HCV) infection, including an 8-week regimen for treatment-naïve patients without cirrhosis and a baseline level of HCV RNA <6 million IU/mL. We analyzed data from a multicenter, prospective, observational study to determine real-world sustained virologic responses 12 weeks after...
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