Article
Management of KRAS-Mutant Non-Small Cell Lung Cancer in the Era of Precision Medicine.
Current treatment options in oncology - 27 Jun 2018
Aredo Jacqueline V, Padda Sukhmani K
Abstract excerpt
OPINION STATEMENT: The discovery of genomic alterations that drive the development and progression of non-small cell lung cancer (NSCLC) has transformed how we treat metastatic disease. However, the promise of precision medicine remains elusive for the most commonly mutated oncogene in NSCLC, KRAS. This is perhaps due to the substantial heterogeneity within the broader genomic context of KRAS-mutant NSCLC. At...
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