The 72Pro Variant of the Tumor Protein 53 Is Associated with an Increased Breast Cancer Risk in the Moroccan Population.

doi:10.1159/000489852

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Article

The 72Pro Variant of the Tumor Protein 53 Is Associated with an Increased Breast Cancer Risk in the Moroccan Population.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 2018

Ayoubi Salah Eddine, Elkarroumi Mohamed, El Khachibi Meryam, Hassani Idrissi Hind, Ayoubi Hasnaa, Ennachit Simohamed, Arazzakou Mounia, Nadifi Sellama

Abstract excerpt

BACKGROUND: The purpose of our case control study is to explore the potential association of tumor protein 53 (TP53) c.215G>C, p. (Arg72Pro) polymorphism (rs1042522) with the risk of breast cancer (BC) development in the Moroccan population. METHODS AND RESULTS: The study population consisted of 125 female patients with confirmed BC and 126 healthy controls. DNA samples were genotyped by Polymerase Chain...

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PMID: 29949804
DOI: 10.1159/000489852

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