Article
A retrospective case study of sunitinib treatment in three patients with Von Hippel-Lindau disease.
Cancer biology & therapy - 1 Jan 2018
Yuan Gang, Liu Qiuli, Tong Dali, Liu Gaolei, Yi Yuting, Zhang Jun, Zhang Yao, Wang Lin-Ang, Wang Luofu, Chen Rongrong, Guan Yanfang, Yi Xin, Lan Weihua, Jiang Jun
Abstract excerpt
Von Hippel-Landau (VHL) disease is characterized by malignant and benign tumors in multiple organs. Sunitinib, a tyrosine kinase inhibitor, has been clinically available for treating sporadic patients with recurrent or unresectable and metastatic clear renal cell carcinomas (cRCCs) and metastatic lesions of the lung, but its effect on VHL disease-associated tumors remains poorly understood. This retrospective...
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