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Article

Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment.

Nature - 1 Jan 2000

Monaco A P, Bertelson C J, Middlesworth W, Colletti C A, Aldridge J, Fischbeck K H, Bartlett R, Pericak-Vance M A, Roses A D, Kunkel L M

Abstract excerpt

The Duchenne muscular dystrophy (DMD) locus has been localized to the short arm of the human X chromosome (Xp21) by detection of structural abnormalities and by genetic linkage studies. A library highly enriched for human DNA from Xp21 was constructed using DNA isolated from a male patient who had a visible deletion and three X-linked disorders (DMD, retinitis pigmentosa and chronic granulomatous disease). Seven...

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Source

Identifiers

PMID: 2993910
DOI: 10.1038/316842a0

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment.PMID 2993910Read ↗

Long-range restriction map around the Duchenne muscular dystrophy gene.Semantic proximity Read ↗

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Identification of new markers in Xp21 between DXS28 (C7) and DMD.Semantic proximity Read ↗

Duplicational mutation at the Duchenne muscular dystrophy locus: its frequency, distribution, origin, and phenotypegenotype correlation.Semantic proximity Read ↗

Direct detection of more than 50% of the Duchenne muscular dystrophy mutations by field inversion gels.Semantic proximity Read ↗

Molecular analysis of human muscular dystrophies.Semantic proximity Read ↗

Detection of an insertion deletion of region 8q13-q21.2 in a patient with Duane syndrome: implications for mapping and cloning a Duane gene.Semantic proximity Read ↗

Analysis of RFLPs and DNA deletions in the Chinese Duchenne muscular dystrophy gene.Semantic proximity Read ↗

Reconstruction of the 2.4 Mb human DMD-gene by homologous YAC recombination.Semantic proximity Read ↗

Deletions, duplications and novel restriction fragment length polymorphism in Duchenne and Becker muscular dystrophies.Semantic proximity Read ↗

Frequency and distribution of deletions in dystrophin gene in Duchenne muscular dystrophy patients from an east-European Slavonic population.Semantic proximity Read ↗

Deletion analysis of Duchenne muscular dystrophy.Semantic proximity Read ↗

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