Article
The First Norovirus Longitudinal Seroepidemiological Study From Sub-Saharan Africa Reveals High Seroprevalence of Diverse Genotypes Associated With Host Susceptibility Factors.
The Journal of infectious diseases - 24 Jul 2018
Thorne Lucy, Nalwoga Angela, Mentzer Alexander J, de Rougemont Alexis, Hosmillo Myra, Webb Emily, Nampiija Margaret, Muhwezi Allan, Carstensen Tommy, Gurdasani Deepti, Hill Adrian V, Sandhu Manj S, Elliott Alison, Goodfellow Ian
Abstract excerpt
Background: Human noroviruses (HuNoVs) are a prominent cause of gastroenteritis, yet fundamental questions remain regarding epidemiology, diversity, and immunity in sub-Saharan African children. We investigated HuNoV seroprevalence and genetic and sociodemographic risk factors in Ugandan children. Methods: We randomly screened 797 participants of a longitudinal birth cohort (Entebbe, EMaBS) and 378 from a...
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