Article
Genotype replacement of the human parainfluenza virus type 2 in Croatia between 2011 and 2017 - the role of neutralising antibodies.
Epidemiology and infection - 1 Aug 2018
Šantak M, Lang Balija M, Mlinarić Galinović G, Ljubin Sternak S, Vilibić-Čavlek T, Tabain I
Abstract excerpt
Previously we reported on the HPIV2 genotype distribution in Croatia 2011-2014. Here we expand this period up to 2017 and confirm that G1a genotype has replaced G3 genotype from the period 2011-2014. Our hypothesis was that the G1a-to-G3 genotype replacement is an antibody-driven event. A cross-neutralisation with anti-HPIV2 sera specific for either G1a or G3 genotype revealed the presence of genotype-specific...
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