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Phylogenetic analysis of human influenza A/H3N2 viruses isolated in 2015 in Germany indicates significant genetic divergence from vaccine strains.

Archives of virology - 1 Jun 2016

Mostafa Ahmed, Abdelwhab El-Sayed M, Slanina Heiko, Hussein Mohamed A, Kuznetsova Irina, Schüttler Christian G, Ziebuhr John, Pleschka Stephan

Abstract excerpt

Infections by H3N2-type influenza A viruses (IAV) resulted in significant numbers of hospitalization in several countries in 2014-2015, causing disease also in vaccinated individuals and, in some cases, fatal outcomes. In this study, sequence analysis of H3N2 viruses isolated in Germany from 1998 to 2015, including eleven H3N2 isolates collected early in 2015, was performed. Compared to the vaccine strain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26973232
DOI: 10.1007/s00705-016-2815-x

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