Practical unidentifiability of a simple vector-borne disease model: Implications for parameter estimation and intervention assessment

Abstract excerpt

Mathematical modeling has an extensive history in vector-borne disease epidemiology, and is increasingly used for prediction, intervention design, and understanding mechanisms. Many studies rely on parameter estimation to link models and data, and to tailor predictions and counterfactuals to specific settings. However, few studies have formally evaluated whether vector-borne disease models can properly estimate...

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