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Article

Did Zika Virus Mutate to Cause Severe Outbreaks?

Trends in microbiology - 1 Oct 2018

Rossi Shannan L, Ebel Gregory D, Shan Chao, Shi Pei-Yong, Vasilakis Nikos

Abstract excerpt

Zika virus (ZIKV) has challenged the assumed knowledge regarding the pathobiology of flaviviruses. Despite causing sporadic and mild disease in the 50 years since its discovery, Zika virus has now caused multiple outbreaks in dozens of countries worldwide. Moreover, the disease severity in recent outbreaks, with neurological disease in adult and devastating congenital malformations in fetuses, was not previously...

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Identifiers

PMID: 29903417
DOI: 10.1016/j.tim.2018.05.007
PMCID: PMC6160291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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