Article
The E23K and A190A variations of the KCNJ11 gene are associated with early-onset type 2 diabetes and blood pressure in the Chinese population.
Molecular and cellular biochemistry - 1 Jun 2015
Zhuang Langen, Zhao Yu, Zhao Weijing, Li Ming, Yu Ming, Lu Ming, Zhang Rong, Ge Xiaoxu, Zheng Taishan, Li Can, Yin Jun, Yin Jingyuan, Bao Yuqian, Liu Limei, Jia Weiping, Liu Yanjun
Abstract excerpt
Conflicting associations between define (KCNJ11) variations and susceptibility to late-onset (>40 years old) type 2 diabetes mellitus (T2DM) have been reported in different ethnic groups. We investigated whether the E23K (G→A, rs5219) or A190A (C→T, rs5218) variations in KCNJ11 are associated with early-onset T2DM and blood pressure in the Chinese population. Case-control study of 175 unrelated Chinese patients...
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