Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Resveratrol Ameliorates Microcystin-LR-Induced Testis Germ Cell Apoptosis in Rats via SIRT1 Signaling Pathway Activation

9 Jun 2018

Abstract excerpt

Microcystin-leucine arginine (MC-LR), a cyclic heptapeptide produced by cyanobacteria, is a strong reproductive toxin. Studies performed in rat Sertoli cells and Chinese hamster ovary cells have demonstrated typical apoptosis after MC-LR exposure. However, little is known on how to protect against the reproductive toxicity induced by MC-LR. The present study aimed to explore the possible molecular mechanism...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Polyamine Metabolism and Applications
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29890735
DOI: 10.3390/toxins10060235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Resveratrol Ameliorates Microcystin-LR-Induced Testis Germ Cell Apoptosis in Rats via SIRT1 Signaling Pathway ActivationPMID 29890735Read ↗

MC-LR induced apoptosis in human embryonic kidney (HEK293) cells through activation of TNF-R1/RIPK1 pathwaySemantic proximity Read ↗

Microcystin-Leucine Arginine Causes Cytotoxic Effects in Sertoli Cells Resulting in Reproductive Dysfunction in Male MiceSemantic proximity Read ↗

Microcystin-leucine arginine mediates apoptosis and engulfment of Leydig cell by testicular macrophages resulting in reduced serum testosterone levels.Semantic proximity Read ↗

Resveratrol Targets a Variety of Oncogenic and Oncosuppressive Signaling for Ovarian Cancer Prevention and TreatmentSemantic proximity Read ↗

Mechanisms of Apoptotic Effects Induced by Resveratrol, Dibenzoylmethane, and Their Analogues on Human Lung Carcinoma CellsSemantic proximity Read ↗

Toxicarioside O induces protective autophagy in a sirtuin-1-dependent manner in colorectal cancer cellsSemantic proximity Read ↗

Investigation of BAX and BCL2 expression and apoptosis in a resveratrol- and prednisolone-treated human T-ALL cell line, CCRF-CEMSemantic proximity Read ↗

N-(3-oxo-acyl) homoserine lactone induced germ cell apoptosis and suppressed the over-activated RAS/MAPK tumorigenesis via mitochondrial-dependent ROS in C. elegans.Semantic proximity Read ↗

Taurine Alleviated Acrylamide-Induced Ovarian Toxicity via Suppression of Stress and Apoptosis in MiceSemantic proximity Read ↗

Resveratrol enhanced mitochondrial recovery from cryopreservation‐induced damages in oocytes and embryosSemantic proximity Read ↗

Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cellsSemantic proximity Read ↗

Fluorochloridone Induces Autophagy in TM4 Sertoli Cells:Involvement of ROS-mediated AKT-mTOR Signaling PathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.