Article
Spotlight on olaparib in the treatment of BRCA-mutated ovarian cancer: design, development and place in therapy.
Drug design, development and therapy - 1 Jan 2018
Lorusso Domenica, Tripodi Elisa, Maltese Giuseppa, Lepori Stefano, Sabatucci Ilaria, Bogani Giorgio, Raspagliesi Francesco
Abstract excerpt
Epithelial ovarian cancer is the sixth most common cancer among women worldwide and the first cause of death among gynecological malignancies. Most of the patients present recurrent disease and unfortunately cannot be cured. The unsatisfactory results obtained with salvage chemotherapy have elicited investigators to search for novel biological agents capable of achieving a better control of the disease. In the...
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